MLB Scores and Standings Thursday, September 23, 1915
| Cleveland Indians | 4 | Final |
| Boston Red Sox | 5 |
| W | Smoky Joe Wood (15-4) |
| L | Ed Klepfer (2-6) |
| S | Carl Mays (5) |
| Cleveland Indians | 2 | Final |
| Boston Red Sox | 6 |
| W | Ernie Shore (18-8) |
| L | Lynn Brenton (1-3) |
| Newark Pepper | 1 | Final |
| Chicago Whales | 2 |
| W | Mordecai Brown (17-8) |
| L | Earl Moseley (15-14) |
| Newark Pepper | 2 | Final |
| Chicago Whales | 1 |
| W | Tom Seaton (14-16) |
| L | George McConnell (23-10) |
| Philadelphia Phillies | 5 | Final |
| Chicago Cubs | 1 |
| W | Grover Alexander (30-10) |
| L | Karl Adams (1-9) |
| Philadelphia Phillies | 3 | Final |
| Chicago Cubs | 2 |
| W | Eppa Rixey (11-11) |
| L | Phil Douglas (7-11) |
| Brooklyn Dodgers | 3 | Final |
| Cincinnati Reds | 2 |
| W | Jeff Pfeffer (18-12) |
| L | Fred Toney (16-6) |
| Brooklyn Tip-Tops | 3 | Final |
| Kansas City Packers | 0 |
| W | Dan Marion (11-8) |
| L | Dan Adams (0-2) |
| St. Louis Browns | 0 | Final |
| New York Yankees | 7 |
| W | George Mogridge (2-2) |
| L | Tom Phillips (1-2) |
| St. Louis Browns | 1 | Final |
| New York Yankees | 5 |
| W | Cliff Markle (1-0) |
| L | Red Hoff (2-2) |
| Detroit Tigers | 6 | Final |
| Philadelphia Athletics | 5 |
| W | Grover Lowdermilk (13-18) |
| L | Tom Sheehan (4-8) |
| S | Red Oldham (4) |
| Boston Braves | 4 | Final |
| Pittsburgh Pirates | 8 |
| W | Wilbur Cooper (5-16) |
| L | Dick Rudolph (21-18) |
| Buffalo Blues | 5 | Final |
| Pittsburgh Rebels | 2 |
| W | Al Schulz (21-13) |
| L | Elmer Knetzer (15-13) |
| Baltimore Terrapins | 2 | Final |
| St. Louis Terriers | 10 |
| W | Eddie Plank (19-11) |
| L | Rankin Johnson (9-14) |
| S | Ed Willett (2) |
| New York Giants | 7 | Final |
| St. Louis Cardinals | 3 |
| W | Jeff Tesreau (18-15) |
| L | Slim Sallee (13-16) |
| Chicago White Sox | 2 | Final |
| Washington Nationals | 1 |
| W | Jim Scott (22-11) |
| L | Harry Harper (3-3) |
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