MLB Scores and Standings Wednesday, September 15, 1965
| Detroit Tigers | 2 | Final |
| Baltimore Orioles | 3 |
| W | Dave McNally (9-6) |
| L | Denny McLain (12-6) |
| Cleveland Indians | 8 | Final |
| Boston Red Sox | 4 |
| W | Steve Hargan (4-3) |
| L | Dennis Bennett (5-4) |
| Chicago White Sox | 8 | Final |
| California Angels | 1 |
| W | John Buzhardt (12-7) |
| L | George Brunet (8-11) |
| Chicago White Sox | 1 | Final |
| California Angels | 2 | (14) |
| W | Ed Sukla (2-3) |
| L | Eddie Fisher (14-7) |
| Los Angeles Dodgers | 6 | Final |
| Chicago Cubs | 8 |
| W | Dick Ellsworth (14-14) |
| L | Howie Reed (6-5) |
| S | Billy Hoeft (1) |
| San Francisco Giants | 3 | Final |
| Houston Astros | 2 |
| W | Frank Linzy (8-2) |
| L | Dave Giusti (7-6) |
| Kansas City Athletics | 5 | Final |
| Minnesota Twins | 7 |
| W | Johnny Klippstein (8-3) |
| L | John Wyatt (2-5) |
| S | Bill Pleis (4) |
| Cincinnati Reds | 2 | Final |
| New York Mets | 1 |
| W | Jim Maloney (19-7) |
| L | Jack Fisher (8-21) |
| Milwaukee Braves | 4 | Final |
| Philadelphia Phillies | 2 |
| W | Tony Cloninger (22-9) |
| L | Chris Short (17-10) |
| S | Dan Osinski (5) |
| St. Louis Cardinals | 7 | Final |
| Pittsburgh Pirates | 3 |
| W | Ray Sadecki (5-13) |
| L | Bob Veale (16-11) |
| S | Nelson Briles (4) |
| New York Yankees | 5 | Final |
| Washington Senators | 3 |
| W | Mel Stottlemyre (18-8) |
| L | Pete Craig (0-2) |
Standings Up to and Including this Date
AL Overall
NL Overall
| Tm | W | L | GB | RS | RA | pythW-L% | |
|---|---|---|---|---|---|---|---|
| SFG | 86 | 59 | .593 | -- | 619 | 505 | .592 |
| CIN | 83 | 63 | .568 | 3.5 | 764 | 642 | .579 |
| LAD | 82 | 64 | .562 | 4.5 | 557 | 504 | .546 |
| MLN | 80 | 65 | .552 | 6.0 | 649 | 577 | .554 |
| PIT | 79 | 69 | .534 | 8.5 | 620 | 552 | .553 |
| PHI | 75 | 69 | .521 | 10.5 | 586 | 615 | .478 |
| STL | 72 | 73 | .497 | 14.0 | 640 | 624 | .512 |
| CHC | 67 | 81 | .453 | 20.5 | 587 | 660 | .447 |
| HOU | 61 | 86 | .415 | 26.0 | 527 | 635 | .416 |
| NYM | 46 | 102 | .311 | 41.5 | 456 | 691 | .319 |
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