MLB Scores and Standings Saturday, September 18, 1915
| Detroit Tigers | 0 | Final |
| Boston Red Sox | 1 | (12) |
| W | Ernie Shore (17-8) |
| L | Harry Coveleski (21-12) |
| Buffalo Blues | 1 | Final |
| Chicago Whales | 0 |
| W | Hugh Bedient (16-16) |
| L | Mike Prendergast (12-11) |
| Brooklyn Dodgers | 7 | Final |
| Chicago Cubs | 1 |
| W | Jack Coombs (14-10) |
| L | Karl Adams (1-8) |
| Philadelphia Phillies | 4 | Final |
| Cincinnati Reds | 2 |
| W | Erskine Mayer (19-14) |
| L | Gene Dale (18-13) |
| Newark Pepper | 5 | Final |
| Kansas City Packers | 6 |
| W | Pete Henning (7-12) |
| L | George Kaiserling (12-13) |
| Newark Pepper | 1 | Final |
| Kansas City Packers | 0 |
| W | Ed Reulbach (17-10) |
| L | Nick Cullop (18-11) |
| Chicago White Sox | 7 | Final |
| New York Yankees | 3 |
| W | Joe Benz (13-10) |
| L | Dazzy Vance (0-3) |
| Chicago White Sox | 4 | Final |
| New York Yankees | 1 |
| W | Reb Russell (10-10) |
| L | George Mogridge (1-2) |
| Cleveland Indians | 5 | Final |
| Philadelphia Athletics | 7 |
| W | Bill Morrisette (1-0) |
| L | Ed Klepfer (2-4) |
| Cleveland Indians | 5 | Final |
| Philadelphia Athletics | 1 |
| W | Fritz Coumbe (4-7) |
| L | Harry Weaver (0-1) |
| New York Giants | 2 | Final |
| Pittsburgh Pirates | 8 |
| W | Al Mamaux (21-7) |
| L | Christy Mathewson (8-14) |
| New York Giants | 7 | Final |
| Pittsburgh Pirates | 2 |
| W | Jeff Tesreau (17-15) |
| L | Erv Kantlehner (5-11) |
| Baltimore Terrapins | 4 | Final |
| Pittsburgh Rebels | 5 | (11) |
| W | Cy Barger (9-6) |
| L | George Suggs (13-17) |
| Baltimore Terrapins | 2 | Final |
| Pittsburgh Rebels | 6 | (5) |
| W | Elmer Knetzer (15-12) |
| L | Charlie Young (1-1) |
| Brooklyn Tip-Tops | 3 | Final |
| St. Louis Terriers | 4 | (12) |
| W | Eddie Plank (17-10) |
| L | Jim Bluejacket (10-10) |
| Brooklyn Tip-Tops | 2 | Final |
| St. Louis Terriers | 5 | (7) |
| W | Eddie Plank (18-10) |
| L | Joseph Finneran (10-12) |
| Boston Braves | 20 | Final |
| St. Louis Cardinals | 1 |
| W | Dick Rudolph (20-17) |
| L | Dan Griner (5-11) |
| S | Jesse Barnes (1) |
| Boston Braves | 6 | Final |
| St. Louis Cardinals | 3 |
| W | Pat Ragan (16-12) |
| L | Slim Sallee (13-15) |
| St. Louis Browns | 0 | Final |
| Washington Nationals | 1 |
| W | Bert Gallia (15-10) |
| L | Tom Phillips (1-1) |
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